Big Earth Data in Support of the Sustainable Development Goals 2019 presents 27 cases studies of CASEarth on the development of the Sustainable Development Goals indicators and sustainability assessments in six SDGs. These cases provide in-depth, systematic research and evaluation results on the selected SDGs and indicators by means of data, method models, and decision support at global, regional, national and local scales. The 27 case studies covered 20 indicators, with focus varying from constructing databases, building index systems, and evaluating indicator progress.